re:Focus contains Gastrodin, a major compound found in Gastrodia elata that research shows exerts significant anti-ADHD e?ects. Ingredients 60 x 500 mg capsules Ingredients Ophiopogon japonicus Paeonia lactiflora Ziziphus jujuba Coptis chinensis Polygala tenuifolia Phellodendron amurense Anemone altaica Gastrodia elata Does not contain:Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts Actions & Indications ActionsAnti-inflammatory downregulates TNF, IL6.Regulation of monoamine neurotransmittersAntioxidationAntianxietyNeuron protectionIndicationsHyperactivity ADHDAttention Deficit ADHDSuggested Use: 1 capsule twice dailyCautions and Contraindications:CYP450Can be combined with Ritalin Gastrodin might reduce the metabolic rate of CYP450-metabolized therapeutic drugs for ADHD, and the combination of gastrodin with these drugs might have a synergistic effect.Results suggested that gastrodin might down-regulate CYP1A1 expression. It was speculated that a beneficial interaction existed between the CYP450-metabolized therapeutic drugs for ADHD and gastrodin. Specifically, gastrodin might reduce the metabolic rate of these drugs in vivo by inhibiting CYP1A1 activity, thereby improving their efficacy (3).