Calcitriol Information

Pronunciation

kal si TRYE ole

What is this drug used for?

• It is used to control low blood calcium levels in certain patients.

• It is used to treat high parathyroid hormone levels in certain patients.

• It may be given to you for other reasons. Talk with the doctor.

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• High calcium like weakness, confusion, fatigue, headache, nausea and vomiting, constipation, or bone pain.

• Fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, abnormal heartbeat, severe dizziness, passing out, fast heartbeat, increased thirst, seizures, loss of strength and energy, lack of appetite, unable to pass urine or change in amount of urine passed, dry mouth, dry eyes, or nausea or vomiting.

• Passing a lot of urine

• Metallic taste

• Abdominal pain

• Eye irritation

• Weight loss

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Storage and Stability

Oral capsule, injection, solution: Store at room temperature of 15°C to 30°C (59°F to 86°F). Protect from light.

Adverse Reactions

Cardiovascular: Cardiac arrhythmia, hypertension

Central nervous system: Apathy, drowsiness, headache, hyperthermia, metallic taste, psychosis, sensory disturbance

Dermatologic: Erythema, erythema multiforme, pruritus, skin rash, urticaria

Endocrine & metabolic: Albuminuria, calcinosis, decreased libido, dehydration, growth suppression, hypercalcemia, hypercholesterolemia, polydipsia, weight loss

Gastrointestinal: Abdominal pain, anorexia, constipation, nausea, pancreatitis, stomach pain, vomiting, xerostomia

Genitourinary: Hypercalciuria, nocturia, urinary tract infection

Hepatic: Increased serum ALT, increased serum AST

Hypersensitivity: Hypersensitivity reaction

Local: Pain at injection site (mild)

Neuromuscular & skeletal: Dystrophy, myalgia, ostealgia, weakness

Ophthalmic: Conjunctivitis, photophobia

Renal: Calcium nephrolithiasis, increased blood urea nitrogen, increased serum creatinine, polyuria

Respiratory: Rhinorrhea

Rare but important or life-threatening: Agitation, anaphylaxis, apprehension, hypermagnesemia, hyperphosphatemia, hypervitaminosis D, increased hematocrit, increased hemoglobin, increased neutrophils, increased serum alkaline phosphatase, insomnia, limb pain, lymphocytosis